In this work, three dimensional NiO nanowrinkles (3D NiO-NWs) were prepared and used as electrode materials to modify the surface of a Glassy carbon electrode (3D NiO-NWs/GCE). Then, differential pulse voltammetry (DPV), cyclic voltammetry (CV) and chronoamperometry (CHA) were employed to determine the electrochemical response of theophylline on as-fabricated sensor. The electrochemical theophylline oxidation was elevated on the modified electrode. The peak current on the modified electrode in phosphate buffer solution (PBS, 0.1 M, pH=7.0) showed a linear elevation with an increase in the theophylline concentration (0.1-900.0 µM), with a narrow detection limit of 0.03±0.001 µM.

In this study, tranexamic acid (Txa) (in 0.1 M Sulfuric acid) modified Glassy carbon electrode (GC) was tested, for the first time, as a sensor for determining the most consumed pain reliever, paracetamol (ACOP) by differential pulse voltammetry (DPV). The tranexamic acid-modified Glassy carbon (rTxa/GC) electrode was characterized by a scanning electron microscope (SEM). Cyclic voltammetry (CV), linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS) (in aqueous and nonaqueous solution) were used to evaluate the electrochemical performance of electrodes. The modified electrode increased the oxidation peak current of ACOP significantly in this case. The experimental results provide that rTxa/GC electrode displayed excellent electrocatalytic response to the oxidation ACOP. Additionally, the rTxa/GC electrode exhibited excellent electrocatalytic activity for the electrochemical determination of ACOP in Britton-Robinson (BR) buffer solution with pH values ranging from 2 to 12. As a result, the effective electroactive surface area of rTxa/GC electrode increased by using a BR buffer solution with pH 6. The linear range was 25 – 80 μM for ACOP with a limit of detection (LOD) of 4.7 μM and a limit of detection (LOQ) of 14.2 μM.

In this study a facile approach to employ Copper nanoparticle (CuNPs) and multi-walled carbon nanotubes (MWCNT) as the nanomaterial for selective detection of asulam have been investigated. This work reports the electrocatalytic oxidation of asulam on Glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (MWCNT), ionic liquids (IL), chitosan (Chit) and copper nanoparticles (CuNPs). Using the proposed nanocomposite provides a specific platform with increased surface. The surface morphology of this modified electrode was characterized by fieldemission scanning electron microscopy (FE-SEM) and energy dispersive X-ray spectrometer (EDX) techniques. The electrochemical behaviors of the fabricated sensor were investigated by cyclic voltammetry (CV) and chronoamperometry modes. Under optimal conditions, the amperometric study exhibits two linear ranges of 1– 11 and 11– 200 μ mol L-1 with a detection limit (LOD) of 0. 33 nmol L-1 (at an S/N of 3) and sensitivity of 1. 9 nA μ mol L-1 for Asulam determination. This novel sensor was used to analyze the real sample. The sensor provides a convenient, low-cost and simple method for Asulam detection and proposes new horizons for quantitative detection of Asulam.